Published 2023-04-17
Keywords
- COVID-19,
- infection,
- Ecuador,
- rheumatic diseases
How to Cite
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Abstract
Objective: To determine the risk factors associated with hospitalization for COVID-19 in patients with rheumatic diseases.
Materials and methods: Observational, retrospective study in patients diagnosed with rheumatic diseases infected by the SARS-CoV-2 virus treated at the IRHED Medical Specialties Center, Luis Vernaza de Guayaquil Hospital, Teodoro Maldonado Carbo Hospital and IESS Ceibos North Hospital from March 2020 to December 2022.
Results: Of the 130 individuals, 108 (83%) were women, with a mean age of 49.58 ± 14.24 years. Age, systemic lupus erythematosus (SLE) and systemic sclerosis showed a significant positive association for hospitalization (r=0.229; p=0.009), (r=0.308; p<0.001), (r=0.183; p=0.038), respectively. Among the comorbidities, liver cirrhosis (r=0.190; p<0.031), chronic kidney disease with glomerular filtration rate <30mL/min (r=0.315; p<0.001), congestive heart failure (r=0.221; p=0.012) showed positive bilateral association for hospitalization. Regarding ICU admission, age (r=0.230; p=0.008), male sex (r=0.230; p=0.008), liver cirrhosis (r=0.244; p=0.005), chronic kidney disease with glomerular filtration <30mL /min (r=0.441; p<0.001), HBP (r=0.206; p=0.019), DM2 (r=0.208; p=0.018), congestive heart failure (r=0.303; p<0.001) showed a significant positive association bilateral. The factors related to death were age (r=0.235; p=0.007) and SLE (r=0.287; p=0.001). Vaccinated patients showed significant bilateral negative association (r=-0.207; p=0.023).
Conclusion: Vaccinated patients with rheumatic diseases have a lower probability of hospitalization.